Set the scene for a crowd-pleasing event at Hyatt Regency Greenville. Our prime location on Main Street, in the heart of downtown Greenville, is an excellent choice for hosting meetings, events, weddings, and more. Choose from 17 flexible meeting and event venues that span 35,000 square feet of space. For our largest affairs, we offer the gorgeous Grand Regency Ballroom, the largest hotel ballroom in Upstate South Carolina. We also have executive boardrooms, intimate salons, an eight-story atrium, and dazzling outdoor spaces. The professional event staff will help ensure your function is a resounding success, every step of the way.