Feel at Home in our Hotel, 3 Blocks from the Mayo Clinic

Make yourself at home and enjoy a visit to Rochester with ideal proximity to the Mayo Clinic. At Hyatt House Rochester / Mayo Clinic Area, your stay with us offers the luxury of spacious rooms, a relaxed pace, access to the Clinic, the Mayo Civic Convention Center, major universities, dining, shopping, and more, all with care, ease, and convenience.

  • Free Internet Access
  • Fitness Center
  • Pool
  • Pet Friendly
  • Business Services
  • Laundry
  • Meeting Facilities
World of Hyatt Business Credit Card

Earn up to 60,000 Bonus Points

Plus, 1 free night each year with the World of Hyatt Credit Card


Hyatt House King Studio Suite
Hyatt House King Bed

Feel comfortable and self-care in spacious, extended-stay rooms featuring a Cozy Corner with sofa-sleeper and fully equipped kitchenettes. Enjoy lush views of Central Park and a bustling downtown Rochester from our fourth-floor terrace.

Our Hotel

24/7 Workout Room

Fitness Center

24/7 Workout Room

Stay active during your Rochester trip with the cardio machines and free weights inside our workout center – the room is accessible 24/7. Looking to swim laps to get your workout? Head to our indoor pool.

Business Center

Hyatt House Business Center

Business Center

We offer free public computers in the Commons of Hyatt House. Remote-print documents for easy pickup, or log into one of two workstations to revise presentations, review documents, and send emails.

Indoor Pool

Family Pool

Indoor Pool

Swim laps, float around, or kick back on a poolside lounger. Our indoor pool is ideal for self-care relaxation or a spirited workout. With a maximum depth of four and half feet, it's also a great family spot.
H Bar


Sip and snack at H Bar, serving a selection of premium quality cocktails, beer, and wine.
Patio Dog


Pets are welcome at Hyatt House Rochester / Mayo Clinic Area. We allow dogs and cats up to 50 pounds. A non-refundable cleaning deposit of $100 on stays 14 nights or less.  For stays longer than 14 nights, the cleaning fee to be determined by management. A maximum of two animals per room.  


1–14 nights: $75 + $100 additional deep-cleaning fee

14+ nights: $250 plus an additional deep cleaning fee determined by management

Weight Limits

We limit pets to two (2) household dogs or cats with a combined weight not to exceed 50 pounds.
What else is happening at Hyatt House Rochester / Mayo Clinic Area?

Travel with the World of Hyatt App.

We're bringing flexibility and peace of mind to your stay, with digital amenities that can help put you in control of how you connect with us. Discover the below amenities via the World of Hyatt app, available at Hyatt House Rochester / Mayo Clinic Area:

  • Account access
  • Points balance & earned rewards
  • Curated meditations from Headspace
  • Hotel stay bill
  • Hotel favorites
  • In-stay benefits